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Reference Guide
Chemical Compatibility
2,000+ chemicals and fluids rated across nine elastomeric compounds — instantly searchable and filterable by material and rating.
Chemical Resistance Reference
Acid and Chemical Resistant Seals — Find the Right Material
Industrial sealing failures happen when the wrong elastomer meets the wrong fluid. Whether you're sealing against aggressive acids, solvents, fuels, steam, hydraulic fluids, refrigerants, or high-pH process chemicals, material selection is the most critical decision you'll make. This guide covers 2,000+ chemicals and fluids rated across nine elastomeric compounds — from general-purpose Buna-N to high-performance AFLAS and FFKM — so you can confirm compatibility before you order. For detailed temperature ranges, FDA compliance, and application guidance for each compound, see our full material information guide.
Chemical Compatibility
Materials & Ratings
Click a material to add/remove it from the table. Use ratings to filter results when materials are selected.
Filter by rating (optional)
Tip: Start typing (e.g., acetone, brake fluid, ammonia).
Best Choice (Good+): “Best Choice” identifies the most commonly recommended material among the nine compounds in this guide, considering compatibility along with practical factors like typical applications, availability, and cost. It is shown only where at least one material is rated Good or better, and the bubble is colored by that material’s own rating — green for Excellent, blue for Good. It indicates the best available option in this guide; it is not a warranty that the material is suitable for your application.
No Recommendation: Where no material in this guide rates Good or better for a fluid, no material is named. This does not mean a sealing solution doesn’t exist — non-elastomeric options such as PTFE may be appropriate, and some applications require a different approach entirely. Please contact us so we can review the application with you.
Disclaimer: Compatibility ratings are a general reference compiled from published industry data and are provided for informational purposes only. Actual performance varies with concentration, temperature, pressure, exposure time, cyclic or dynamic duty, hardware design, and other application specifics, and ratings may not reflect every grade or compound of a given material. Nothing in this guide constitutes a warranty, express or implied, of merchantability or fitness for a particular purpose. Final material selection and validation for a given service remain the responsibility of the user. For aggressive, high-purity, high-temperature, or safety-critical applications, confirm material selection with our team before ordering.
No Recommendation: Where no material in this guide rates Good or better for a fluid, no material is named. This does not mean a sealing solution doesn’t exist — non-elastomeric options such as PTFE may be appropriate, and some applications require a different approach entirely. Please contact us so we can review the application with you.
Disclaimer: Compatibility ratings are a general reference compiled from published industry data and are provided for informational purposes only. Actual performance varies with concentration, temperature, pressure, exposure time, cyclic or dynamic duty, hardware design, and other application specifics, and ratings may not reflect every grade or compound of a given material. Nothing in this guide constitutes a warranty, express or implied, of merchantability or fitness for a particular purpose. Final material selection and validation for a given service remain the responsibility of the user. For aggressive, high-purity, high-temperature, or safety-critical applications, confirm material selection with our team before ordering.
Need help selecting the right material?
If you're unsure about compatibility or don't see what you need, send us your application details and we'll help confirm the right compound.
Or reach us at sales@alliedseals.com or 847-673-2080.
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